Cellular Analyses
Cytotoxicity Testing
Measurement of the effect of a test substance on cell viability. Dose–response curves and IC50 calculation for drug candidates, biomedical products and dental materials.
About the service
Assessing the potential toxic effects of candidate drug compounds and biomaterials on cells is a critical step in developing safe and effective therapies. Our specialists analyse parameters such as cell viability, membrane integrity and metabolic activity using a range of methods, setting out in detail the dose–response relationship of the tested substances and their mechanisms of action. This clarifies the safety profile early in your project and helps you minimise the risks you might otherwise meet later on.
Scope
- Colorimetric viability assays (MTT and similar methods)
- Determination of the dose–response relationship
- Measurement of cell viability and metabolic activity
- Toxicity assessment across different cell types
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